Removing water from the blood decreases the volume of fluid circulating through the blood vessels. This subsequently decreases the pressure within the blood vessels. Diuretics are therefore used to lower high blood pressure. Although indapamide is classed as a diuretic, it also lowers blood pressure through a direct action on the blood vessels. Indapamide causes the blood vessels to widen, which reduces the pressure inside the blood vessels. This helps to lower blood pressure.
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